TY - JOUR
T1 - Redistribution of synaptic vesicles during long-term potentiation in the hippocampus
AU - Applegate, Michael D.
AU - Kerr, Douglas S.
AU - Landfield, Philip W.
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1987/1/20
Y1 - 1987/1/20
N2 - Synaptic vesicles were quantified 20 min after the induction of long-term potentiation (LTP) in the Schaffer-commissural system of the hippocampus. With LTP, significant increases were found in vesicles attached to the active zone membrane, and in the percentage of vesicles adjacent to the active zone. In addition, as others have reported, overall vesicle density was decreased and spine area was increased. These results suggest that an increased probability of vesicle may contribute to brain LTP.
AB - Synaptic vesicles were quantified 20 min after the induction of long-term potentiation (LTP) in the Schaffer-commissural system of the hippocampus. With LTP, significant increases were found in vesicles attached to the active zone membrane, and in the percentage of vesicles adjacent to the active zone. In addition, as others have reported, overall vesicle density was decreased and spine area was increased. These results suggest that an increased probability of vesicle may contribute to brain LTP.
KW - Dendritic spine
KW - Hippocampus
KW - Long-term potentiation
KW - Presynaptic
KW - Stereology
KW - Synaptic vesicle
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U2 - 10.1016/0006-8993(87)91429-6
DO - 10.1016/0006-8993(87)91429-6
M3 - Article
C2 - 3028579
AN - SCOPUS:0023073715
SN - 0006-8993
VL - 401
SP - 401
EP - 406
JO - Brain Research
JF - Brain Research
IS - 2
ER -