Repurposing of metformin and aspirin by targeting AMPK-mTOR and inflammation for pancreatic cancer prevention and treatment

Medicine and Dentistry

• Pancreas Cancer 100%
• Glycon 100%
• Mammalian Target of Rapamycin 100%
• Acetylsalicylic Acid 100%
• Hydroxymethylglutaryl Coenzyme A Reductase Kinase 100%
• Cancer 33%
• Cell Signaling Pathway 33%
• Malignant Neoplasm 16%
• Carcinogenesis 16%
• Antiinflammatory Activity 16%
• Survival Rate 16%
• Catenin 16%
• Chemoprevention 16%
• Notch 16%
• mTOR Signaling 16%
• Action Potential 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Repurposing 100%
• Pancreas Cancer 100%
• Metformin 100%
• Hydroxymethylglutaryl Coenzyme A Reductase Kinase 100%
• Acetylsalicylic Acid 100%
• Inflammation 100%
• Malignant Neoplasm 33%
• Anti-Inflammatory Drug 16%
• Catenin 16%
• Survival Rate 16%
• Carcinogenesis 16%