Risperidone half-life in a patient taking paroxetine: A case report

J. Barnhill; M. T. Susce; F. J. Diaz; Jose De Leon

doi:10.1055/s-2005-873159

Risperidone half-life in a patient taking paroxetine: A case report

J. Barnhill
, M. T. Susce
, F. J. Diaz
, Jose De Leon

Producción científica: Article › revisión exhaustiva

9 Citas (Scopus)

Resumen

This case report further establishes the inhibitory effects of paroxetine on risperidone (R) metabolism in a patient whose R was discontinued due to side effects. Baseline through levels in ng/ml were 33 for R, 9 for 9-hydroxyrisperidone (9-OHR) and 42 for the total moiety. The fourth morning after R discontinuation, levels were 4 for R, 1 for 9-OHR and 5 for the total moiety. The estimated half-lives were 23.8 hours for R, 22.8 hours for 9-OHR and 23.5 hours for the total moiety.

Idioma original	English
Páginas (desde-hasta)	223-225
Número de páginas	3
Publicación	Pharmacopsychiatry
Volumen	38
N.º	5
DOI	https://doi.org/10.1055/s-2005-873159
Estado	Published - sept 2005

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Good health and well being

ASJC Scopus subject areas

Psychiatry and Mental health
Pharmacology (medical)

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abstract = "This case report further establishes the inhibitory effects of paroxetine on risperidone (R) metabolism in a patient whose R was discontinued due to side effects. Baseline through levels in ng/ml were 33 for R, 9 for 9-hydroxyrisperidone (9-OHR) and 42 for the total moiety. The fourth morning after R discontinuation, levels were 4 for R, 1 for 9-OHR and 5 for the total moiety. The estimated half-lives were 23.8 hours for R, 22.8 hours for 9-OHR and 23.5 hours for the total moiety.",

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AU - Susce, M. T.

AU - Diaz, F. J.

AU - De Leon, Jose

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ER -

Risperidone half-life in a patient taking paroxetine: A case report

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