Serum zinc levels and Alzheimer's disease

L. L. Rulon; J. D. Robertson; M. A. Lovell; M. A. Deibel; W. D. Ehmann; W. R. Markesbery

doi:10.1385/BTER:75:1-3:79

Serum zinc levels and Alzheimer's disease

L. L. Rulon
, J. D. Robertson
, M. A. Lovell
, M. A. Deibel
, W. D. Ehmann
, W. R. Markesbery

Producción científica: Article › revisión exhaustiva

68 Citas (Scopus)

Resumen

Concentrations of zinc in postmortem serum and four brain regions were measured by flame atomic absorption spectrometry and instrumental neutron activation analysis, respectively, in nine Alzheimer's disease (AD) and eight control subjects. A statistically significant elevation of zinc serum was observed in AD subjects (136.4 ± 66.8 μg/dL) compared with age-matched control subjects (71.1 ± 35.0 μg/dL). No significant differences were observed between AD and control zinc concentrations in the amygdala, hippocampus, cerebellum, and superior and middle temporal gryi.

Idioma original	English
Páginas (desde-hasta)	79-85
Número de páginas	7
Publicación	Biological Trace Element Research
Volumen	75
N.º	1-3
DOI	https://doi.org/10.1385/BTER:75:1-3:79
Estado	Published - 2000

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ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Biochemistry
Clinical Biochemistry
Inorganic Chemistry
Biochemistry, medical

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abstract = "Concentrations of zinc in postmortem serum and four brain regions were measured by flame atomic absorption spectrometry and instrumental neutron activation analysis, respectively, in nine Alzheimer's disease (AD) and eight control subjects. A statistically significant elevation of zinc serum was observed in AD subjects (136.4 ± 66.8 μg/dL) compared with age-matched control subjects (71.1 ± 35.0 μg/dL). No significant differences were observed between AD and control zinc concentrations in the amygdala, hippocampus, cerebellum, and superior and middle temporal gryi.",

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AU - Rulon, L. L.

AU - Robertson, J. D.

AU - Lovell, M. A.

AU - Deibel, M. A.

AU - Ehmann, W. D.

AU - Markesbery, W. R.

PY - 2000

Y1 - 2000

N2 - Concentrations of zinc in postmortem serum and four brain regions were measured by flame atomic absorption spectrometry and instrumental neutron activation analysis, respectively, in nine Alzheimer's disease (AD) and eight control subjects. A statistically significant elevation of zinc serum was observed in AD subjects (136.4 ± 66.8 μg/dL) compared with age-matched control subjects (71.1 ± 35.0 μg/dL). No significant differences were observed between AD and control zinc concentrations in the amygdala, hippocampus, cerebellum, and superior and middle temporal gryi.

AB - Concentrations of zinc in postmortem serum and four brain regions were measured by flame atomic absorption spectrometry and instrumental neutron activation analysis, respectively, in nine Alzheimer's disease (AD) and eight control subjects. A statistically significant elevation of zinc serum was observed in AD subjects (136.4 ± 66.8 μg/dL) compared with age-matched control subjects (71.1 ± 35.0 μg/dL). No significant differences were observed between AD and control zinc concentrations in the amygdala, hippocampus, cerebellum, and superior and middle temporal gryi.

KW - Alzheimer's disease

KW - Brain

KW - FAAS

KW - INAA

KW - Serum

KW - Zinc

UR - https://www.scopus.com/pages/publications/0033911861

UR - https://www.scopus.com/pages/publications/0033911861#tab=citedBy

U2 - 10.1385/BTER:75:1-3:79

DO - 10.1385/BTER:75:1-3:79

M3 - Article

C2 - 11051598

AN - SCOPUS:0033911861

SN - 0163-4984

VL - 75

SP - 79

EP - 85

JO - Biological Trace Element Research

JF - Biological Trace Element Research

IS - 1-3

ER -

Serum zinc levels and Alzheimer's disease

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