Stable Isotope-Resolved Metabolomics by NMR

Penghui Lin; Andrew N. Lane; Teresa W.M. Fan

doi:10.1007/978-1-4939-9690-2_9

Stable Isotope-Resolved Metabolomics by NMR

Penghui Lin, Andrew N. Lane, Teresa W.M. Fan

Producción científica: Chapter › revisión exhaustiva

15 Citas (Scopus)

Resumen

Stable isotopes enable the tracing of atoms from precursors to products via metabolic transformations in situ and in crude extracts. NMR has some unique capabilities that are especially suited for metabolic analysis, including atom position-resolved isotope analysis and isotope editing. In this chapter we describe NMR-based analysis of positional isotopomer distribution using metabolic tracers.

Idioma original	English
Título de la publicación alojada	Methods in Molecular Biology
Páginas	151-168
Número de páginas	18
DOI	https://doi.org/10.1007/978-1-4939-9690-2_9
Estado	Published - 2019

Serie de la publicación

Nombre	Methods in Molecular Biology
Volumen	2037
ISSN (versión impresa)	1064-3745
ISSN (versión digital)	1940-6029

Nota bibliográfica

Publisher Copyright:
© Springer Science+Business Media, LLC, part of Springer Nature 2019.

Financiación

This work was supported in part by NIH grants 1U24DK097215-01A1, CA163223-01A1, 5P20GM121327 (COBRE) the Carmen L. Buck endowment (to ANL), and the Edith D. Gardner Chair in Cancer Research (TWMF).

Financiadores	Número del financiador
National Institutes of Health (NIH)	1U24DK097215-01A1, CA163223-01A1
National Institutes of Health (NIH)
National Institute of General Medical Sciences DP2GM119177 Sophie Dumont National Institute of General Medical Sciences	P20GM121327
National Institute of General Medical Sciences DP2GM119177 Sophie Dumont National Institute of General Medical Sciences

ASJC Scopus subject areas

Molecular Biology
Genetics

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KW - Quantification

KW - Spectral editing

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Stable Isotope-Resolved Metabolomics by NMR

Resumen

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Financiación

ASJC Scopus subject areas

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