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Structural Isomerization of 2-Anilinonicotinic Acid Leads to a New Synthon in 6-Anilinonicotinic Acids

  • Siqing Peng
  • , Faquan Yu
  • , Danrui Xu
  • , Conggang Li
  • , Sean R. Parkin
  • , Tonglei Li
  • , Mingtao Zhang
  • , Sihui Long

Producción científica: Article › revisión exhaustiva

3 Citas (Scopus)

Resumen

Through structural modification of 2-anilinonicotinic acid by isomerization, a new synthon, acid-aminopyridine, is created, and the two original synthons, i.e., the acid-acid homosynthon and acid-pyridine heterosynthon are no longer observed in the newly designed 6-anilinonicotinic acids. The new synthon has a hydrogen-bond strength rivaling that of the acid-acid homosynthon and the acid-pyridine heterosynthon, as suggested by theoretical calculations, which explains its formation.

Idioma originalEnglish
Páginas (desde-hasta)4849-4859
Número de páginas11
PublicaciónCrystal Growth and Design
Volumen18
N.º9
DOI
EstadoPublished - sept 5 2018

Nota bibliográfica

Publisher Copyright:
Copyright © 2018 American Chemical Society.

Financiación

S.P. and S.L. thank Natural Science Foundation of Hubei Province (2014CFB787) and the President’s Fund of Wuhan Institute of Technology (CX2016075) for financial support.

FinanciadoresNúmero del financiador
Natural Science Foundation of Hubei Province2014CFB787
Natural Science Foundation of Hubei Province
Wuhan Institute of TechnologyCX2016075
Wuhan Institute of Technology

    ASJC Scopus subject areas

    • General Chemistry
    • General Materials Science
    • Condensed Matter Physics

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