Suppression of growth and transformation and induction of apoptosis by EGR-1

Chaoting Liu; Vivek M. Rangnekar; Eileen Adamson; Dan Mercola

Suppression of growth and transformation and induction of apoptosis by EGR-1

Chaoting Liu
, Vivek M. Rangnekar
, Eileen Adamson
, Dan Mercola

Producción científica: Article › revisión exhaustiva

221 Citas (Scopus)

Resumen

Although cloned as an "immediate-early gene," recent studies show that EGR-1 functions in growth regulation and suppression of transformation by transactivation of the transforming growth factor β-1 (TGF-β1) gene and cooperation with Sp1, Jun-B, p21^WAFl/Cip1, and stimulates apoptosis by transactivation of the p53 gene.

Idioma original	English
Páginas (desde-hasta)	3-28
Número de páginas	26
Publicación	Cancer Gene Therapy
Volumen	5
N.º	1
Estado	Published - 1998

Financiación

Financiadores	Número del financiador
National Childhood Cancer Registry – National Cancer Institute	R01CA063783
National Childhood Cancer Registry – National Cancer Institute

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Good health and well being

ASJC Scopus subject areas

Molecular Medicine
Molecular Biology
Cancer Research

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title = "Suppression of growth and transformation and induction of apoptosis by EGR-1",

abstract = "Although cloned as an {"}immediate-early gene,{"} recent studies show that EGR-1 functions in growth regulation and suppression of transformation by transactivation of the transforming growth factor β-1 (TGF-β1) gene and cooperation with Sp1, Jun-B, p21WAFl/Cip1, and stimulates apoptosis by transactivation of the p53 gene.",

keywords = "Cancer, EGR-1, Sp1, Transformation, Transforming growth factor β-1, WT1",

author = "Chaoting Liu and Rangnekar, \{Vivek M.\} and Eileen Adamson and Dan Mercola",

year = "1998",

language = "English",

volume = "5",

pages = "3--28",

number = "1",

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TY - JOUR

T1 - Suppression of growth and transformation and induction of apoptosis by EGR-1

AU - Liu, Chaoting

AU - Rangnekar, Vivek M.

AU - Adamson, Eileen

AU - Mercola, Dan

PY - 1998

Y1 - 1998

N2 - Although cloned as an "immediate-early gene," recent studies show that EGR-1 functions in growth regulation and suppression of transformation by transactivation of the transforming growth factor β-1 (TGF-β1) gene and cooperation with Sp1, Jun-B, p21WAFl/Cip1, and stimulates apoptosis by transactivation of the p53 gene.

AB - Although cloned as an "immediate-early gene," recent studies show that EGR-1 functions in growth regulation and suppression of transformation by transactivation of the transforming growth factor β-1 (TGF-β1) gene and cooperation with Sp1, Jun-B, p21WAFl/Cip1, and stimulates apoptosis by transactivation of the p53 gene.

KW - Cancer

KW - EGR-1

KW - Sp1

KW - Transformation

KW - Transforming growth factor β-1

KW - WT1

UR - https://www.scopus.com/pages/publications/0031602586

UR - https://www.scopus.com/pages/publications/0031602586#tab=citedBy

M3 - Article

C2 - 9476963

AN - SCOPUS:0031602586

SN - 0929-1903

VL - 5

SP - 3

EP - 28

JO - Cancer Gene Therapy

JF - Cancer Gene Therapy

IS - 1

ER -

Suppression of growth and transformation and induction of apoptosis by EGR-1

Resumen

Financiación

ODS de las Naciones Unidas

ASJC Scopus subject areas

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