TY - JOUR
T1 - Synthesis and structure of 5,7-dimethylthieno[3,4-d]pyridazine
AU - Tice, Nathan C.
AU - Peak, Sarah M.
AU - Parkin, Sean
PY - 2010
Y1 - 2010
N2 - The reaction of 2,5-dimethylthiophene-3,4-dicarboxaldehye (3) with excess hydrazine hydrate afforded the desired 5,6-fused ring thiophene derivative, 5,7-dimethylthieno[3,4-d]pyridazine (4), in high yield (82%). Pyridazine 4 was characterized spectroscopically and its structure was confirmed by X-ray crystallography. Compound 4 was observed to have an inverted, coplanar stacking arrangement in the solid state.
AB - The reaction of 2,5-dimethylthiophene-3,4-dicarboxaldehye (3) with excess hydrazine hydrate afforded the desired 5,6-fused ring thiophene derivative, 5,7-dimethylthieno[3,4-d]pyridazine (4), in high yield (82%). Pyridazine 4 was characterized spectroscopically and its structure was confirmed by X-ray crystallography. Compound 4 was observed to have an inverted, coplanar stacking arrangement in the solid state.
UR - https://www.scopus.com/pages/publications/79751494791
UR - https://www.scopus.com/inward/citedby.url?scp=79751494791&partnerID=8YFLogxK
U2 - 10.3987/COM-10-11940
DO - 10.3987/COM-10-11940
M3 - Article
AN - SCOPUS:79751494791
SN - 0385-5414
VL - 81
SP - 1631
EP - 1639
JO - Heterocycles
JF - Heterocycles
IS - 7
ER -