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The Circadian Variations in Systemic Blood Pressure, Ocular Perfusion Pressure, and Ocular Blood Flow: Risk Factors for Glaucoma?

  • Adam Werne
  • , Alon Harris
  • , Danny Moore
  • , Itay BenZion
  • , Brent Siesky

Producción científica: Review articlerevisión exhaustiva

63 Citas (Scopus)

Resumen

Intraocular pressure, a major risk factor for glaucoma, is known to vary throughout the day, yet glaucoma continues to progress in some patients despite it being well controlled. It is important to understand how other glaucomatous risk factors are affected by circadian variations. The purpose of this review is to analyze the literature concerning circadian variations in systemic blood pressure, ocular perfusion pressure, and ocular blood flow and to identify consensus findings regarding their impact on glaucoma. This review suggests that nonphysiologic nocturnal blood pressure dipping and wider circadian fluctuations in ocular perfusion pressure are linked with the development and progression of glaucoma. No consensus concerning circadian variations in ocular blood flow exists in the current literature, and future investigations of nocturnal changes in blood flow and glaucoma progression are required.

Idioma originalEnglish
Páginas (desde-hasta)559-567
Número de páginas9
PublicaciónSurvey of Ophthalmology
Volumen53
N.º6
DOI
EstadoPublished - nov 2008

Financiación

The authors reported no proprietary or commercial interest in any product mentioned or concept discussed in this article. This work was supported by an unrestricted grant from Research to Prevent Blindness, Inc and by the International Research Scholar Award from Research to Prevent Blindness, Inc.

Financiadores
Research to Prevent Blindness

    ASJC Scopus subject areas

    • Ophthalmology

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