The cytolethal distending toxin family

Carol L. Pickett; Chris A. Whitehouse

doi:10.1016/S0966-842X(99)01537-1

The cytolethal distending toxin family

Carol L. Pickett
, Chris A. Whitehouse

Microbiology, Immunology, and Molecular Genetics

Producción científica: Review article › revisión exhaustiva

214 Citas (Scopus)

Resumen

Cytolethal distending toxins are produced by a small but diverse group of bacterial pathogens. This newly discovered toxin family can cause a variety of mammalian cells to become irreversibly blocked in the G2 phase of the cell cycle. How this novel effect is accomplished is unknown but the study of these fascinating toxins promises to reveal new methods of host-pathogen interaction. Copyright (C) 1999 Elsevier Science Ltd.

Idioma original	English
Páginas (desde-hasta)	292-297
Número de páginas	6
Publicación	Trends in Microbiology
Volumen	7
N.º	7
DOI	https://doi.org/10.1016/S0966-842X(99)01537-1
Estado	Published - jul 1 1999

Nota bibliográfica

Funding Information:
We thank Eric Hansen, James Kaper, Lawrence Dreyfus, Eric Oswald, Nancy Strockbine and Daniel Scott for stimulating discussions and the NIH for financial support (AI41477).

Financiación

We thank Eric Hansen, James Kaper, Lawrence Dreyfus, Eric Oswald, Nancy Strockbine and Daniel Scott for stimulating discussions and the NIH for financial support (AI41477).

Financiadores	Número del financiador
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases	R01AI041477

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Good health and well being

ASJC Scopus subject areas

Microbiology
Microbiology (medical)
Virology
Infectious Diseases

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title = "The cytolethal distending toxin family",

abstract = "Cytolethal distending toxins are produced by a small but diverse group of bacterial pathogens. This newly discovered toxin family can cause a variety of mammalian cells to become irreversibly blocked in the G2 phase of the cell cycle. How this novel effect is accomplished is unknown but the study of these fascinating toxins promises to reveal new methods of host-pathogen interaction. Copyright (C) 1999 Elsevier Science Ltd.",

author = "Pickett, \{Carol L.\} and Whitehouse, \{Chris A.\}",

note = "Funding Information: We thank Eric Hansen, James Kaper, Lawrence Dreyfus, Eric Oswald, Nancy Strockbine and Daniel Scott for stimulating discussions and the NIH for financial support (AI41477).",

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AU - Pickett, Carol L.

AU - Whitehouse, Chris A.

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Y1 - 1999/7/1

N2 - Cytolethal distending toxins are produced by a small but diverse group of bacterial pathogens. This newly discovered toxin family can cause a variety of mammalian cells to become irreversibly blocked in the G2 phase of the cell cycle. How this novel effect is accomplished is unknown but the study of these fascinating toxins promises to reveal new methods of host-pathogen interaction. Copyright (C) 1999 Elsevier Science Ltd.

AB - Cytolethal distending toxins are produced by a small but diverse group of bacterial pathogens. This newly discovered toxin family can cause a variety of mammalian cells to become irreversibly blocked in the G2 phase of the cell cycle. How this novel effect is accomplished is unknown but the study of these fascinating toxins promises to reveal new methods of host-pathogen interaction. Copyright (C) 1999 Elsevier Science Ltd.

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DO - 10.1016/S0966-842X(99)01537-1

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The cytolethal distending toxin family

Resumen

Nota bibliográfica

Financiación

ODS de las Naciones Unidas

ASJC Scopus subject areas

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