The role of hot plate and general environmental stimuli in morphine analgesic tolerance

Michael T. Bardo; Paul J. Wellman; Richard A. Hughes

doi:10.1016/0091-3057(81)90145-3

The role of hot plate and general environmental stimuli in morphine analgesic tolerance

Michael T. Bardo
, Paul J. Wellman
, Richard A. Hughes

Producción científica: Article › revisión exhaustiva

13 Citas (Scopus)

Resumen

Rats given one injection of morphine (5 mg/kg) paired with a hot plate test displayed greater analgesic tolerance than rats given nine injections of morphine paired with a distinct room in which the hot plate apparatus was located. Hot plate stimuli, rather than general environmental stimuli, are prepotent in the acquisition of morphine analgesic tolerance assessed by the hot plate procedure.

Idioma original	English
Páginas (desde-hasta)	757-760
Número de páginas	4
Publicación	Pharmacology Biochemistry and Behavior
Volumen	14
N.º	5
DOI	https://doi.org/10.1016/0091-3057(81)90145-3
Estado	Published - may 1981

ASJC Scopus subject areas

Biochemistry
Toxicology
Pharmacology
Clinical Biochemistry
Biological Psychiatry
Behavioral Neuroscience

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title = "The role of hot plate and general environmental stimuli in morphine analgesic tolerance",

abstract = "Rats given one injection of morphine (5 mg/kg) paired with a hot plate test displayed greater analgesic tolerance than rats given nine injections of morphine paired with a distinct room in which the hot plate apparatus was located. Hot plate stimuli, rather than general environmental stimuli, are prepotent in the acquisition of morphine analgesic tolerance assessed by the hot plate procedure.",

keywords = "Hot plate, Morphine analgesia, Morphine tolerance, Rat",

author = "Bardo, \{Michael T.\} and Wellman, \{Paul J.\} and Hughes, \{Richard A.\}",

year = "1981",

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T1 - The role of hot plate and general environmental stimuli in morphine analgesic tolerance

AU - Bardo, Michael T.

AU - Wellman, Paul J.

AU - Hughes, Richard A.

PY - 1981/5

Y1 - 1981/5

N2 - Rats given one injection of morphine (5 mg/kg) paired with a hot plate test displayed greater analgesic tolerance than rats given nine injections of morphine paired with a distinct room in which the hot plate apparatus was located. Hot plate stimuli, rather than general environmental stimuli, are prepotent in the acquisition of morphine analgesic tolerance assessed by the hot plate procedure.

AB - Rats given one injection of morphine (5 mg/kg) paired with a hot plate test displayed greater analgesic tolerance than rats given nine injections of morphine paired with a distinct room in which the hot plate apparatus was located. Hot plate stimuli, rather than general environmental stimuli, are prepotent in the acquisition of morphine analgesic tolerance assessed by the hot plate procedure.

KW - Hot plate

KW - Morphine analgesia

KW - Morphine tolerance

KW - Rat

UR - https://www.scopus.com/pages/publications/0019497516

UR - https://www.scopus.com/pages/publications/0019497516#tab=citedBy

U2 - 10.1016/0091-3057(81)90145-3

DO - 10.1016/0091-3057(81)90145-3

M3 - Article

C2 - 6113609

AN - SCOPUS:0019497516

SN - 0091-3057

VL - 14

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EP - 760

JO - Pharmacology Biochemistry and Behavior

JF - Pharmacology Biochemistry and Behavior

IS - 5

ER -

The role of hot plate and general environmental stimuli in morphine analgesic tolerance

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ASJC Scopus subject areas

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