The role of microRNAs in skeletal muscle health and disease

Tyler J. Kirby; Thomas Chaillou; John J. McCarthy

doi:10.2741/4298

The role of microRNAs in skeletal muscle health and disease

Tyler J. Kirby
, Thomas Chaillou
, John J. McCarthy

Producción científica: Review article › revisión exhaustiva

64 Citas (Scopus)

Resumen

Over the last decade non-coding RNAs have emerged as importance regulators of gene expression. In particular, microRNAs are a class of small RNAs of ∼ 22 nucleotides that repress gene expression through a post-transcriptional mechanism. MicroRNAs have been shown to be involved in a broader range of biological processes, both physiological and pathological, including myogenesis, adaptation to exercise and various myopathies. The purpose of this review is to provide a comprehensive summary of what is currently known about the role of microRNAs in skeletal muscle health and disease.

Idioma original	English
Páginas (desde-hasta)	37-77
Número de páginas	41
Publicación	Frontiers in Bioscience - Landmark
Volumen	20
N.º	1
DOI	https://doi.org/10.2741/4298
Estado	Published - ene 15 2015

Nota bibliográfica

Publisher Copyright:
© 2015, Frontiers in Bioscience. All rights reserved.

Financiación

Financiadores	Número del financiador
National Institute of Arthritis and Musculoskeletal and Skin Diseases	R01AR060701

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology

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10.2741/4298

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The role of microRNAs in skeletal muscle health and disease

Resumen

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ASJC Scopus subject areas

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