The role of the spleen in ischemic stroke

Keith R. Pennypacker; Halina Offner

doi:10.1038/jcbfm.2014.212

The role of the spleen in ischemic stroke

Keith R. Pennypacker
, Halina Offner

Producción científica: Review article › revisión exhaustiva

46 Citas (Scopus)

Resumen

This opinion piece highlights the scientific literature reporting that the peripheral immune response to ischemic stroke originates from the spleen. Removal of the spleen not only reduces stroke-induced neurodegeneration but also cellular degeneration in the body's other tissues when exposed to ischemic conditions.

Idioma original	English
Páginas (desde-hasta)	186-187
Número de páginas	2
Publicación	Journal of Cerebral Blood Flow and Metabolism
Volumen	35
N.º	2
DOI	https://doi.org/10.1038/jcbfm.2014.212
Estado	Published - feb 2 2015

Nota bibliográfica

Publisher Copyright:
© 2015 ISCBFM All rights reserved.

Financiación

Financiadores	Número del financiador
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke	R01NS076013

ASJC Scopus subject areas

Neurology
Clinical Neurology
Cardiology and Cardiovascular Medicine

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10.1038/jcbfm.2014.212

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title = "The role of the spleen in ischemic stroke",

abstract = "This opinion piece highlights the scientific literature reporting that the peripheral immune response to ischemic stroke originates from the spleen. Removal of the spleen not only reduces stroke-induced neurodegeneration but also cellular degeneration in the body's other tissues when exposed to ischemic conditions.",

keywords = "brain ischemia, macrophages, neuroinflammation",

author = "Pennypacker, \{Keith R.\} and Halina Offner",

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AU - Offner, Halina

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KW - brain ischemia

KW - macrophages

KW - neuroinflammation

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UR - https://www.scopus.com/pages/publications/84922013837#tab=citedBy

U2 - 10.1038/jcbfm.2014.212

DO - 10.1038/jcbfm.2014.212

M3 - Review article

C2 - 25465042

AN - SCOPUS:84922013837

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JO - Journal of Cerebral Blood Flow and Metabolism

JF - Journal of Cerebral Blood Flow and Metabolism

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The role of the spleen in ischemic stroke

Resumen

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ASJC Scopus subject areas

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