The structural feature of S1′ subsite of carboxypeptidase A

Dong H. Kim; Yong Soon Shin; Kyung Bo Kim

doi:10.1016/S0960-894X(01)80816-7

The structural feature of S₁′ subsite of carboxypeptidase A

Dong H. Kim
, Yong Soon Shin
, Kyung Bo Kim

Pharmaceutical Sciences

Producción científica: Article › revisión exhaustiva

8 Citas (Scopus)

Resumen

The study on the structural feature of carboxypeptidase A using transition state analog inhibitors suggests that the principal substrate recognition subsite of the enzyme is a pocket-shaped cavity having a rectangular opening with effective dimensions of 3.5 Å × 7.1 Å. The principal substrate recognition subsite (S₁ ′ subsite) of Carboxypeptidase A is a pocket-shaped cavity having a rectangular opening with effective dimensions of 3.5 Å × 7.1 Å.

Idioma original	English
Páginas (desde-hasta)	317-322
Número de páginas	6
Publicación	Bioorganic and Medicinal Chemistry Letters
Volumen	1
N.º	6
DOI	https://doi.org/10.1016/S0960-894X(01)80816-7
Estado	Published - 1991

Nota bibliográfica

Funding Information:
AchowledgmenAt:u thors thank the Ministry of Education,R epublico f Korea for the financial supporto f this workt hrough the Basic ScienceI nstitute at POSTECH. Acknowledgemiesn ta lso duet o Prof. KwangS ooK im who provided molecular dimensions of naphthalenea nd helpful discussion.

Financiación

AchowledgmenAt:u thors thank the Ministry of Education,R epublico f Korea for the financial supporto f this workt hrough the Basic ScienceI nstitute at POSTECH. Acknowledgemiesn ta lso duet o Prof. KwangS ooK im who provided molecular dimensions of naphthalenea nd helpful discussion.

Financiadores
Ministry of Education,R epublico f Korea
Pohang University of Science and Technology

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

Acceder al documento

10.1016/S0960-894X(01)80816-7

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abstract = "The study on the structural feature of carboxypeptidase A using transition state analog inhibitors suggests that the principal substrate recognition subsite of the enzyme is a pocket-shaped cavity having a rectangular opening with effective dimensions of 3.5 {\AA} × 7.1 {\AA}. The principal substrate recognition subsite (S1 ′ subsite) of Carboxypeptidase A is a pocket-shaped cavity having a rectangular opening with effective dimensions of 3.5 {\AA} × 7.1 {\AA}.",

author = "Kim, \{Dong H.\} and Shin, \{Yong Soon\} and Kim, \{Kyung Bo\}",

note = "Funding Information: AchowledgmenAt:u thors thank the Ministry of Education,R epublico f Korea for the financial supporto f this workt hrough the Basic ScienceI nstitute at POSTECH. Acknowledgemiesn ta lso duet o Prof. KwangS ooK im who provided molecular dimensions of naphthalenea nd helpful discussion.",

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AU - Shin, Yong Soon

AU - Kim, Kyung Bo

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