THE WORK OF BREATHING IN A NONLINEAR HUMAN LUNG MODEL

A. Athanasiades; F. Ghorbel; J. W. Clark; S. C. Niranjan; C. H. Liu; J. B. Zwischenberger; A. Bidani

doi:10.1115/IMECE1997-0426

THE WORK OF BREATHING IN A NONLINEAR HUMAN LUNG MODEL

A. Athanasiades
, F. Ghorbel
, J. W. Clark
, S. C. Niranjan
, C. H. Liu
, J. B. Zwischenberger
, A. Bidani

Producción científica: Conference contribution › revisión exhaustiva

Resumen

Work of breathing (WOB) functions associated with the mechanics of breathing are identified, based on a nonlinear model of the human lung and using a Lagrangian approach. Total and dissipative WOB values are computed numerically for three spontaneous breathing maneuvers (tidal, panting and forced vital capacity) of the same subject. An additional simulation reveals the effect of changing lung tissue compliance on WOB. The energy analysis provides valuable insight into the mechanics of respiration. and, in particular, the significance of individual model components. It provides the basis for sensitivity and optimization studies of the respiratory function, especially in the context of evaluating ventilator-dependent patients.

Idioma original	English
Título de la publicación alojada	Dynamic Systems and Control
Páginas	433-438
Número de páginas	6
ISBN (versión digital)	9780791818244
DOI	https://doi.org/10.1115/IMECE1997-0426
Estado	Published - 1997
Evento	ASME 1997 International Mechanical Engineering Congress and Exposition, IMECE 1997 - Dynamic Systems and Control - Dallas, United States Duración: nov 16 1997 → nov 21 1997

Serie de la publicación

Nombre	ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volumen	1997-Q

Conference

Conference	ASME 1997 International Mechanical Engineering Congress and Exposition, IMECE 1997 - Dynamic Systems and Control
País/Territorio	United States
Ciudad	Dallas
Período	11/16/97 → 11/21/97

Nota bibliográfica

Publisher Copyright:
© 1997 American Society of Mechanical Engineers (ASME). All rights reserved.

ASJC Scopus subject areas

Mechanical Engineering

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10.1115/IMECE1997-0426

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@inproceedings{d6e0c374e13a4138a593f096164a5ba3,

title = "THE WORK OF BREATHING IN A NONLINEAR HUMAN LUNG MODEL",

abstract = "Work of breathing (WOB) functions associated with the mechanics of breathing are identified, based on a nonlinear model of the human lung and using a Lagrangian approach. Total and dissipative WOB values are computed numerically for three spontaneous breathing maneuvers (tidal, panting and forced vital capacity) of the same subject. An additional simulation reveals the effect of changing lung tissue compliance on WOB. The energy analysis provides valuable insight into the mechanics of respiration. and, in particular, the significance of individual model components. It provides the basis for sensitivity and optimization studies of the respiratory function, especially in the context of evaluating ventilator-dependent patients.",

author = "A. Athanasiades and F. Ghorbel and Clark, \{J. W.\} and Niranjan, \{S. C.\} and Liu, \{C. H.\} and Zwischenberger, \{J. B.\} and A. Bidani",

note = "Publisher Copyright: {\textcopyright} 1997 American Society of Mechanical Engineers (ASME). All rights reserved.; ASME 1997 International Mechanical Engineering Congress and Exposition, IMECE 1997 - Dynamic Systems and Control ; Conference date: 16-11-1997 Through 21-11-1997",

year = "1997",

doi = "10.1115/IMECE1997-0426",

language = "English",

series = "ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)",

pages = "433--438",

booktitle = "Dynamic Systems and Control",

}

Athanasiades, A, Ghorbel, F, Clark, JW, Niranjan, SC, Liu, CH , Zwischenberger, JB & Bidani, A 1997, THE WORK OF BREATHING IN A NONLINEAR HUMAN LUNG MODEL. En Dynamic Systems and Control. ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE), vol. 1997-Q, pp. 433-438, ASME 1997 International Mechanical Engineering Congress and Exposition, IMECE 1997 - Dynamic Systems and Control, Dallas, United States, 11/16/97. https://doi.org/10.1115/IMECE1997-0426

TY - GEN

T1 - THE WORK OF BREATHING IN A NONLINEAR HUMAN LUNG MODEL

AU - Athanasiades, A.

AU - Ghorbel, F.

AU - Clark, J. W.

AU - Niranjan, S. C.

AU - Liu, C. H.

AU - Zwischenberger, J. B.

AU - Bidani, A.

PY - 1997

Y1 - 1997

N2 - Work of breathing (WOB) functions associated with the mechanics of breathing are identified, based on a nonlinear model of the human lung and using a Lagrangian approach. Total and dissipative WOB values are computed numerically for three spontaneous breathing maneuvers (tidal, panting and forced vital capacity) of the same subject. An additional simulation reveals the effect of changing lung tissue compliance on WOB. The energy analysis provides valuable insight into the mechanics of respiration. and, in particular, the significance of individual model components. It provides the basis for sensitivity and optimization studies of the respiratory function, especially in the context of evaluating ventilator-dependent patients.

AB - Work of breathing (WOB) functions associated with the mechanics of breathing are identified, based on a nonlinear model of the human lung and using a Lagrangian approach. Total and dissipative WOB values are computed numerically for three spontaneous breathing maneuvers (tidal, panting and forced vital capacity) of the same subject. An additional simulation reveals the effect of changing lung tissue compliance on WOB. The energy analysis provides valuable insight into the mechanics of respiration. and, in particular, the significance of individual model components. It provides the basis for sensitivity and optimization studies of the respiratory function, especially in the context of evaluating ventilator-dependent patients.

UR - https://www.scopus.com/pages/publications/85126919112

UR - https://www.scopus.com/pages/publications/85126919112#tab=citedBy

U2 - 10.1115/IMECE1997-0426

DO - 10.1115/IMECE1997-0426

M3 - Conference contribution

AN - SCOPUS:85126919112

T3 - ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)

SP - 433

EP - 438

BT - Dynamic Systems and Control

T2 - ASME 1997 International Mechanical Engineering Congress and Exposition, IMECE 1997 - Dynamic Systems and Control

Y2 - 16 November 1997 through 21 November 1997

ER -

THE WORK OF BREATHING IN A NONLINEAR HUMAN LUNG MODEL

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