Thermally responsive membrane-based microbiological sensing component for early detection of membrane biofouling

Guang Cai; Colleen Gorey; Amr Zaky; Isabel Escobar; Cyndee Gruden

doi:10.1016/j.desal.2010.11.030

Thermally responsive membrane-based microbiological sensing component for early detection of membrane biofouling

Guang Cai, Colleen Gorey, Amr Zaky, Isabel Escobar, Cyndee Gruden

Producción científica: Article › revisión exhaustiva

11 Citas (Scopus)

Resumen

Early detection of bacteria in water treatment is desired to mitigate system biofouling and potential human health impacts. This research involved the development of an antibody-based sensor, which was attached to a hydroxypropyl cellulose (HPC) modified cellulose acetate ultrafiltration membrane surface, to target bacteria. HPC was chosen because it collapses above and expands below a lower critical solution temperature (43. °C), thus allowing temperature modulation. The membrane had a high target recovery efficiency (10-18%) in both single bacterium and complex samples (simulated by adding organics and competitive organisms). Sensor recovery was decreased (to 5-7%) following temperature activation (above 50. °C) due to adverse impacts of temperature on the antibody. The membrane was able to be regenerated (with 0.1. M NaOH) and reused three consecutive times. The thermally responsive sensing membrane developed from this work was specifically developed to detect biofoulants in membrane-based water treatment processes. However, it could be adapted to address a range of environmental detection concerns, such as pathogen detection.

Idioma original	English
Páginas (desde-hasta)	116-123
Número de páginas	8
Publicación	Desalination
Volumen	270
N.º	1-3
DOI	https://doi.org/10.1016/j.desal.2010.11.030
Estado	Published - abr 1 2011

Nota bibliográfica

Funding Information:
We are grateful to DARPA (Grant HR0011-07-1-0003 ) and NSF (CBET 0610624 ) for funding this research. We also wish to express our sincere thanks to Dr Steven Kloos and Ms Jessica Schloss of GE water and Process Technologies for providing membranes.

Financiación

We are grateful to DARPA (Grant HR0011-07-1-0003 ) and NSF (CBET 0610624 ) for funding this research. We also wish to express our sincere thanks to Dr Steven Kloos and Ms Jessica Schloss of GE water and Process Technologies for providing membranes.

Financiadores	Número del financiador
National Science Foundation (NSF)	CBET 0610624
Defense Advanced Research Projects Agency	HR0011-07-1-0003

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering
General Materials Science
Water Science and Technology
Mechanical Engineering

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

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10.1016/j.desal.2010.11.030

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title = "Thermally responsive membrane-based microbiological sensing component for early detection of membrane biofouling",

abstract = "Early detection of bacteria in water treatment is desired to mitigate system biofouling and potential human health impacts. This research involved the development of an antibody-based sensor, which was attached to a hydroxypropyl cellulose (HPC) modified cellulose acetate ultrafiltration membrane surface, to target bacteria. HPC was chosen because it collapses above and expands below a lower critical solution temperature (43. °C), thus allowing temperature modulation. The membrane had a high target recovery efficiency (10-18\%) in both single bacterium and complex samples (simulated by adding organics and competitive organisms). Sensor recovery was decreased (to 5-7\%) following temperature activation (above 50. °C) due to adverse impacts of temperature on the antibody. The membrane was able to be regenerated (with 0.1. M NaOH) and reused three consecutive times. The thermally responsive sensing membrane developed from this work was specifically developed to detect biofoulants in membrane-based water treatment processes. However, it could be adapted to address a range of environmental detection concerns, such as pathogen detection.",

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author = "Guang Cai and Colleen Gorey and Amr Zaky and Isabel Escobar and Cyndee Gruden",

note = "Funding Information: We are grateful to DARPA (Grant HR0011-07-1-0003 ) and NSF (CBET 0610624 ) for funding this research. We also wish to express our sincere thanks to Dr Steven Kloos and Ms Jessica Schloss of GE water and Process Technologies for providing membranes.",

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AU - Cai, Guang

AU - Gorey, Colleen

AU - Zaky, Amr

AU - Escobar, Isabel

AU - Gruden, Cyndee

N1 - Funding Information: We are grateful to DARPA (Grant HR0011-07-1-0003 ) and NSF (CBET 0610624 ) for funding this research. We also wish to express our sincere thanks to Dr Steven Kloos and Ms Jessica Schloss of GE water and Process Technologies for providing membranes.

PY - 2011/4/1

Y1 - 2011/4/1

N2 - Early detection of bacteria in water treatment is desired to mitigate system biofouling and potential human health impacts. This research involved the development of an antibody-based sensor, which was attached to a hydroxypropyl cellulose (HPC) modified cellulose acetate ultrafiltration membrane surface, to target bacteria. HPC was chosen because it collapses above and expands below a lower critical solution temperature (43. °C), thus allowing temperature modulation. The membrane had a high target recovery efficiency (10-18%) in both single bacterium and complex samples (simulated by adding organics and competitive organisms). Sensor recovery was decreased (to 5-7%) following temperature activation (above 50. °C) due to adverse impacts of temperature on the antibody. The membrane was able to be regenerated (with 0.1. M NaOH) and reused three consecutive times. The thermally responsive sensing membrane developed from this work was specifically developed to detect biofoulants in membrane-based water treatment processes. However, it could be adapted to address a range of environmental detection concerns, such as pathogen detection.

AB - Early detection of bacteria in water treatment is desired to mitigate system biofouling and potential human health impacts. This research involved the development of an antibody-based sensor, which was attached to a hydroxypropyl cellulose (HPC) modified cellulose acetate ultrafiltration membrane surface, to target bacteria. HPC was chosen because it collapses above and expands below a lower critical solution temperature (43. °C), thus allowing temperature modulation. The membrane had a high target recovery efficiency (10-18%) in both single bacterium and complex samples (simulated by adding organics and competitive organisms). Sensor recovery was decreased (to 5-7%) following temperature activation (above 50. °C) due to adverse impacts of temperature on the antibody. The membrane was able to be regenerated (with 0.1. M NaOH) and reused three consecutive times. The thermally responsive sensing membrane developed from this work was specifically developed to detect biofoulants in membrane-based water treatment processes. However, it could be adapted to address a range of environmental detection concerns, such as pathogen detection.

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KW - Detection

KW - Membrane

KW - Sensor

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Thermally responsive membrane-based microbiological sensing component for early detection of membrane biofouling

Resumen

Nota bibliográfica

Financiación

ASJC Scopus subject areas

ODS de las Naciones Unidas

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