Thyroid gland volumes in premature infants using serial ultrasounds

Safdar S. Khan; Irene Hong-McAtee; Vesna Martich Kriss; Scott Stevens; Timothy Crawford; Mina Hanna; Henrietta Bada; Nirmala Desai

doi:10.1038/s41372-018-0149-0

Thyroid gland volumes in premature infants using serial ultrasounds

Safdar S. Khan
, Irene Hong-McAtee
, Vesna Martich Kriss
, Scott Stevens
, Timothy Crawford
, Mina Hanna
, Henrietta Bada
, Nirmala Desai

Producción científica: Article › revisión exhaustiva

2 Citas (Scopus)

Resumen

Background: There is a gap in knowledge about the postnatal growth of thyroid gland in preterm infants. Objective: To determine postnatal growth of thyroid gland in preterm infants. Methods: Thyroid gland volume was calculated in 57 prospectively enrolled preterm infants by measuring serial longitudinal, antero-posterior, and transverse dimensions of thyroid gland with ultrasound. Data were analyzed by using the Wilcoxon and independent t test. Results: There was a significant correlation between thyroid volume (TV) and birthweight (BW) (p = 0.01), and between TV and gestational age (p = 0.02). However, unexpectedly, 12 infants had a decrease in TV between the first and second ultrasounds. Infants with late onset bacterial sepsis had lower TVs on their second ultrasounds than infants without sepsis. Conclusions: Thyroid ultrasound in preterm infants provides noninvasive and quick approach to determine TV and morphology. TV in preterm infants correlates positively with BW and gestational age. However, postnatal growth of thyroid gland is variable and may seemingly be affected by postnatal factors.

Idioma original	English
Páginas (desde-hasta)	1353-1358
Número de páginas	6
Publicación	Journal of Perinatology
Volumen	38
N.º	10
DOI	https://doi.org/10.1038/s41372-018-0149-0
Estado	Published - oct 1 2018

Nota bibliográfica

Publisher Copyright:
© 2018, Nature America, Inc., part of Springer Nature.

Financiación

Acknowledgements The project described was supported by Children’s Miracle Network (CMN) grant awarded to Kentucky Children’s Hospital. We thank our research nurses Vicky Whitehead and Deb Grider for their assistance. We thank parents, nurses and doctors at Kentucky Children’s hospital for their contribution in completion of this study. Funding The project described was supported by the Children’s Miracle Network (CMN) grant awarded to Kentucky Children’s Hospital.

Financiadores
Kentucky Children’s Hospital
Children’s Miracle Network
Kentucky Children’s Hospital
Children’s Miracle Network

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1038/s41372-018-0149-0

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title = "Thyroid gland volumes in premature infants using serial ultrasounds",

abstract = "Background: There is a gap in knowledge about the postnatal growth of thyroid gland in preterm infants. Objective: To determine postnatal growth of thyroid gland in preterm infants. Methods: Thyroid gland volume was calculated in 57 prospectively enrolled preterm infants by measuring serial longitudinal, antero-posterior, and transverse dimensions of thyroid gland with ultrasound. Data were analyzed by using the Wilcoxon and independent t test. Results: There was a significant correlation between thyroid volume (TV) and birthweight (BW) (p = 0.01), and between TV and gestational age (p = 0.02). However, unexpectedly, 12 infants had a decrease in TV between the first and second ultrasounds. Infants with late onset bacterial sepsis had lower TVs on their second ultrasounds than infants without sepsis. Conclusions: Thyroid ultrasound in preterm infants provides noninvasive and quick approach to determine TV and morphology. TV in preterm infants correlates positively with BW and gestational age. However, postnatal growth of thyroid gland is variable and may seemingly be affected by postnatal factors.",

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AU - Hong-McAtee, Irene

AU - Kriss, Vesna Martich

AU - Stevens, Scott

AU - Crawford, Timothy

AU - Hanna, Mina

AU - Bada, Henrietta

AU - Desai, Nirmala

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N2 - Background: There is a gap in knowledge about the postnatal growth of thyroid gland in preterm infants. Objective: To determine postnatal growth of thyroid gland in preterm infants. Methods: Thyroid gland volume was calculated in 57 prospectively enrolled preterm infants by measuring serial longitudinal, antero-posterior, and transverse dimensions of thyroid gland with ultrasound. Data were analyzed by using the Wilcoxon and independent t test. Results: There was a significant correlation between thyroid volume (TV) and birthweight (BW) (p = 0.01), and between TV and gestational age (p = 0.02). However, unexpectedly, 12 infants had a decrease in TV between the first and second ultrasounds. Infants with late onset bacterial sepsis had lower TVs on their second ultrasounds than infants without sepsis. Conclusions: Thyroid ultrasound in preterm infants provides noninvasive and quick approach to determine TV and morphology. TV in preterm infants correlates positively with BW and gestational age. However, postnatal growth of thyroid gland is variable and may seemingly be affected by postnatal factors.

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Thyroid gland volumes in premature infants using serial ultrasounds

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Financiación

ASJC Scopus subject areas

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