Thyrotropin-Releasing Hormone for Spinal Trauma

To the Editor: The results of Faden et al. with dexamethasone treatment for spinal trauma (October 29 issue¹) are at odds with the results obtained in at least three other laboratories in the past 12 years. In addition, two more recent studies (not cited by Faden et al.) of the efficacy of a glucocorticoid (methylprednisolone) for induced blunt trauma to the spinal cord^{2 , 3} have suggested the need for steroid doses that are much higher than those used by previous investigators or by Faden et al. Most impressive are the results of Means et al.,³ who have shown that cats. . .