Towards quality assurance and quality control in untargeted metabolomics studies

Richard D. Beger; Warwick B. Dunn; Abbas Bandukwala; Bianca Bethan; David Broadhurst; Clary B. Clish; Surendra Dasari; Leslie Derr; Annie Evans; Steve Fischer; Thomas Flynn; Thomas Hartung; David Herrington; Richard Higashi; Ping Ching Hsu; Christina Jones; Maureen Kachman; Helen Karuso; Gary Kruppa; Katrice Lippa; Padma Maruvada; Jonathan Mosley; Ioanna Ntai; Claire O’Donovan; Mary Playdon; Daniel Raftery; Daniel Shaughnessy; Amanda Souza; Timothy Spaeder; Barbara Spalholz; Fariba Tayyari; Baljit Ubhi; Mukesh Verma; Tilman Walk; Ian Wilson; Keren Witkin; Daniel W. Bearden; Krista A. Zanetti

doi:10.1007/s11306-018-1460-7

Towards quality assurance and quality control in untargeted metabolomics studies

Richard D. Beger
, Warwick B. Dunn
, Abbas Bandukwala
, Bianca Bethan
, David Broadhurst
, Clary B. Clish
, Surendra Dasari
, Leslie Derr
, Annie Evans
, Steve Fischer
, Thomas Flynn
, Thomas Hartung
, David Herrington
, Richard Higashi
, Ping Ching Hsu
, Christina Jones
, Maureen Kachman
, Helen Karuso
, Gary Kruppa
, Katrice Lippa

Padma Maruvada, Jonathan Mosley, Ioanna Ntai, Claire O’Donovan, Mary Playdon, Daniel Raftery, Daniel Shaughnessy, Amanda Souza, Timothy Spaeder, Barbara Spalholz, Fariba Tayyari, Baljit Ubhi, Mukesh Verma, Tilman Walk, Ian Wilson, Keren Witkin, Daniel W. Bearden, Krista A. Zanetti

Toxicology and Cancer Biology

Producción científica: Article › revisión exhaustiva

127 Citas (Scopus)

Resumen

We describe here the agreed upon first development steps and priority objectives of a community engagement effort to address current challenges in quality assurance (QA) and quality control (QC) in untargeted metabolomic studies. This has included (1) a QA and QC questionnaire responded to by the metabolomics community in 2015 which recommended education of the metabolomics community, development of appropriate standard reference materials and providing incentives for laboratories to apply QA and QC; (2) a 2-day ‘Think Tank on Quality Assurance and Quality Control for Untargeted Metabolomic Studies’ held at the National Cancer Institute’s Shady Grove Campus and (3) establishment of the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) to drive forward developments in a coordinated manner.

Idioma original	English
Número de artículo	4
Publicación	Metabolomics
Volumen	15
N.º	1
DOI	https://doi.org/10.1007/s11306-018-1460-7
Estado	Published - ene 1 2019

Nota bibliográfica

Publisher Copyright:
© 2019, Springer Science+Business Media, LLC, part of Springer Nature.

Financiación

Financiadores	Número del financiador
National Institute of Diabetes and Digestive and Kidney Diseases	P30DK017047
National Institute of Diabetes and Digestive and Kidney Diseases

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Biochemistry
Clinical Biochemistry

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

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10.1007/s11306-018-1460-7

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Beger, R. D., Dunn, W. B., Bandukwala, A., Bethan, B., Broadhurst, D., Clish, C. B., Dasari, S., Derr, L., Evans, A., Fischer, S., Flynn, T., Hartung, T., Herrington, D., Higashi, R., Hsu, P. C., Jones, C., Kachman, M., Karuso, H., Kruppa, G., ... Zanetti, K. A. (2019). Towards quality assurance and quality control in untargeted metabolomics studies. Metabolomics, 15(1), Artículo 4. https://doi.org/10.1007/s11306-018-1460-7

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abstract = "We describe here the agreed upon first development steps and priority objectives of a community engagement effort to address current challenges in quality assurance (QA) and quality control (QC) in untargeted metabolomic studies. This has included (1) a QA and QC questionnaire responded to by the metabolomics community in 2015 which recommended education of the metabolomics community, development of appropriate standard reference materials and providing incentives for laboratories to apply QA and QC; (2) a 2-day {\textquoteleft}Think Tank on Quality Assurance and Quality Control for Untargeted Metabolomic Studies{\textquoteright} held at the National Cancer Institute{\textquoteright}s Shady Grove Campus and (3) establishment of the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) to drive forward developments in a coordinated manner.",

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note = "Publisher Copyright: {\textcopyright} 2019, Springer Science+Business Media, LLC, part of Springer Nature.",

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Beger, RD, Dunn, WB, Bandukwala, A, Bethan, B, Broadhurst, D, Clish, CB, Dasari, S, Derr, L, Evans, A, Fischer, S, Flynn, T, Hartung, T, Herrington, D, Higashi, R, Hsu, PC, Jones, C, Kachman, M, Karuso, H, Kruppa, G, Lippa, K, Maruvada, P, Mosley, J, Ntai, I, O’Donovan, C, Playdon, M, Raftery, D, Shaughnessy, D, Souza, A, Spaeder, T, Spalholz, B, Tayyari, F, Ubhi, B, Verma, M, Walk, T, Wilson, I, Witkin, K, Bearden, DW & Zanetti, KA 2019, 'Towards quality assurance and quality control in untargeted metabolomics studies', Metabolomics, vol. 15, n.º 1, 4. https://doi.org/10.1007/s11306-018-1460-7

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AU - Beger, Richard D.

AU - Dunn, Warwick B.

AU - Bandukwala, Abbas

AU - Bethan, Bianca

AU - Broadhurst, David

AU - Clish, Clary B.

AU - Dasari, Surendra

AU - Derr, Leslie

AU - Evans, Annie

AU - Fischer, Steve

AU - Flynn, Thomas

AU - Hartung, Thomas

AU - Herrington, David

AU - Higashi, Richard

AU - Hsu, Ping Ching

AU - Jones, Christina

AU - Kachman, Maureen

AU - Karuso, Helen

AU - Kruppa, Gary

AU - Lippa, Katrice

AU - Maruvada, Padma

AU - Mosley, Jonathan

AU - Ntai, Ioanna

AU - O’Donovan, Claire

AU - Playdon, Mary

AU - Raftery, Daniel

AU - Shaughnessy, Daniel

AU - Souza, Amanda

AU - Spaeder, Timothy

AU - Spalholz, Barbara

AU - Tayyari, Fariba

AU - Ubhi, Baljit

AU - Verma, Mukesh

AU - Walk, Tilman

AU - Wilson, Ian

AU - Witkin, Keren

AU - Bearden, Daniel W.

AU - Zanetti, Krista A.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - We describe here the agreed upon first development steps and priority objectives of a community engagement effort to address current challenges in quality assurance (QA) and quality control (QC) in untargeted metabolomic studies. This has included (1) a QA and QC questionnaire responded to by the metabolomics community in 2015 which recommended education of the metabolomics community, development of appropriate standard reference materials and providing incentives for laboratories to apply QA and QC; (2) a 2-day ‘Think Tank on Quality Assurance and Quality Control for Untargeted Metabolomic Studies’ held at the National Cancer Institute’s Shady Grove Campus and (3) establishment of the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) to drive forward developments in a coordinated manner.

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KW - Community engagement

KW - Quality assurance (QA)

KW - Quality control (QC)

KW - Reporting metrics

KW - Test materials

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UR - https://www.scopus.com/pages/publications/85058797585#tab=citedBy

U2 - 10.1007/s11306-018-1460-7

DO - 10.1007/s11306-018-1460-7

M3 - Article

C2 - 30830465

AN - SCOPUS:85058797585

SN - 1573-3882

VL - 15

JO - Metabolomics

JF - Metabolomics

IS - 1

M1 - 4

ER -

Towards quality assurance and quality control in untargeted metabolomics studies

Resumen

Nota bibliográfica

Financiación

ASJC Scopus subject areas

ODS de las Naciones Unidas

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