Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER

Neuroscience

• Microtubules 100%
• Potassium Channel 100%
• Long QT Syndrome 100%
• Endoplasmic Reticulum 100%
• Glycoprotein 33%
• Glycosylation 33%
• G Protein 16%
• Vesicular Stomatitis Virus 16%
• Missense Mutation 16%
• Chaperone 16%
• Voltage-Gated Potassium Channel 16%
• Calnexin 16%
• Temperature Sensitive Mutant 16%
• Myocyte 16%

Biochemistry, Genetics and Molecular Biology

• Quality Control 100%
• Potassium Channel 100%
• Long QT Syndrome 100%
• Glycosylation 33%
• Glycoprotein 33%
• Golgi Apparatus 33%
• Wild Type 16%
• Subcellular Localization 16%
• Nocodazole 16%
• Vesiculovirus 16%
• Voltage-Gated Potassium Channels 16%
• Missense Mutation 16%
• Temperature Sensitive Mutant 16%
• Cardiac Muscle Cell 16%
• Calnexin 16%
• G Protein 16%

Immunology and Microbiology

• Microtubule 100%
• Potassium Channels 100%
• Endoplasmic reticulum 100%
• Glycoprotein 40%
• Glycosylation 40%
• Cellular Distribution 20%
• Temperature Sensitive Mutant 20%
• Missense Mutation 20%
• Voltage-Gated Potassium Channel 20%
• Wild Type 20%
• Cardiac Muscle Cell 20%
• Calnexin 20%
• Vesiculovirus 20%