Tumor Necrosis Factor Receptors: A Brief Digestion

Yiwei Lin; Zhibing Duan; Binhua P. Zhou

doi:10.1016/B978-0-12-821618-7.00162-0

Tumor Necrosis Factor Receptors: A Brief Digestion

Producción científica: Chapter › revisión exhaustiva

Resumen

Members of the tumor necrosis factor receptor superfamily (TNFRSF) play essential roles in tissue development and homeostasis. Through unique receptor–ligand interaction, TNFRSF members become activated and recruit intracellular adaptor proteins to initiate diverse signaling pathways mediating cell survival, proliferation, differentiation, and apoptosis. Deregulation of TNFR pathways is associated with inflammatory and autoimmune disorders as well as cancer. Therapeutic strategies of targeting TNFRSF members and their ligands have been developed.

Idioma original	English
Título de la publicación alojada	Encyclopedia of Cell Biology
Subtítulo de la publicación alojada	Volume 1-6, Second Edition
Páginas	78-84
Número de páginas	7
Volumen	4
ISBN (versión digital)	9780128216248
DOI	https://doi.org/10.1016/B978-0-12-821618-7.00162-0
Estado	Published - ene 1 2022

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© 2023 Elsevier Inc. All rights reserved.

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ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/B978-0-12-821618-7.00162-0

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KW - Signal transduction

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BT - Encyclopedia of Cell Biology

ER -

Tumor Necrosis Factor Receptors: A Brief Digestion

Resumen

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ODS de las Naciones Unidas

ASJC Scopus subject areas

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