Vaginal progesterone reduces the risk of preterm birth and adverse perinatal outcomes in singleton gestations with a midtrimester sonographic short cervix (≤25 mm): an updated individual patient data meta-analysis

Roberto Romero; Agustin Conde-Agudelo; Eduardo da Fonseca; John M. O'Brien; George W. Creasy; Sonia S. Hassan; Kypros H. Nicolaides

doi:10.1016/j.ajog.2025.03.013

Vaginal progesterone reduces the risk of preterm birth and adverse perinatal outcomes in singleton gestations with a midtrimester sonographic short cervix (≤25 mm): an updated individual patient data meta-analysis

Roberto Romero
, Agustin Conde-Agudelo
, Eduardo da Fonseca
, John M. O'Brien
, George W. Creasy
, Sonia S. Hassan
, Kypros H. Nicolaides

Producción científica: Article › revisión exhaustiva

9 Citas (Scopus)

Idioma original	English
Páginas (desde-hasta)	e1-e5
Publicación	American Journal of Obstetrics and Gynecology
Volumen	233
N.º	1
DOI	https://doi.org/10.1016/j.ajog.2025.03.013
Estado	Published - jul 2025

Financiación

This work was supported, in part, by the Pregnancy Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, United States Department of Health and Human Services (NICHD/NIH/DHHS); and, in part, by federal funds from NICHD/NIH/DHHS (Contract No. HHSN275201300006C). The funder had no role in the design or conduct of the study; collection, management, analysis, or interpretation of the data; preparation, review or approval of the manuscript or the decision to submit the manuscript for publication.

Financiadores	Número del financiador
National Institute of Child Health and Human Development
Eunice Kennedy Shriver National Institute of Child Health and Human Development
National Institutes of Health (NIH)
Division of Intramural Research
U.S. Department of Health and Human Services	HHSN275201300006C

ASJC Scopus subject areas

Obstetrics and Gynecology

Acceder al documento

10.1016/j.ajog.2025.03.013

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Romero, R., Conde-Agudelo, A., da Fonseca, E., O'Brien, J. M., Creasy, G. W., Hassan, S. S., & Nicolaides, K. H. (2025). Vaginal progesterone reduces the risk of preterm birth and adverse perinatal outcomes in singleton gestations with a midtrimester sonographic short cervix (≤25 mm): an updated individual patient data meta-analysis. American Journal of Obstetrics and Gynecology, 233(1), e1-e5. https://doi.org/10.1016/j.ajog.2025.03.013

Romero, Roberto ; Conde-Agudelo, Agustin ; da Fonseca, Eduardo et al. / Vaginal progesterone reduces the risk of preterm birth and adverse perinatal outcomes in singleton gestations with a midtrimester sonographic short cervix (≤25 mm) : an updated individual patient data meta-analysis. En: American Journal of Obstetrics and Gynecology. 2025 ; Vol. 233, N.º 1. pp. e1-e5.

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Romero, R, Conde-Agudelo, A, da Fonseca, E, O'Brien, JM, Creasy, GW, Hassan, SS & Nicolaides, KH 2025, 'Vaginal progesterone reduces the risk of preterm birth and adverse perinatal outcomes in singleton gestations with a midtrimester sonographic short cervix (≤25 mm): an updated individual patient data meta-analysis', American Journal of Obstetrics and Gynecology, vol. 233, n.º 1, pp. e1-e5. https://doi.org/10.1016/j.ajog.2025.03.013

Vaginal progesterone reduces the risk of preterm birth and adverse perinatal outcomes in singleton gestations with a midtrimester sonographic short cervix (≤25 mm): an updated individual patient data meta-analysis. / Romero, Roberto; Conde-Agudelo, Agustin; da Fonseca, Eduardo et al.
En: American Journal of Obstetrics and Gynecology, Vol. 233, N.º 1, 07.2025, p. e1-e5.

Producción científica: Article › revisión exhaustiva

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Romero R, Conde-Agudelo A, da Fonseca E, O'Brien JM, Creasy GW, Hassan SS et al. Vaginal progesterone reduces the risk of preterm birth and adverse perinatal outcomes in singleton gestations with a midtrimester sonographic short cervix (≤25 mm): an updated individual patient data meta-analysis. American Journal of Obstetrics and Gynecology. 2025 jul;233(1):e1-e5. doi: 10.1016/j.ajog.2025.03.013